I-123/I-131 Metaiodobenzylguanidine in Theranostics
نویسندگان
چکیده
منابع مشابه
درمان تومورهای غددی-عصبی با I-131 Metaiodobenzylguanidine (I-131 MIBG)
زمینه: کاربرد رادیودارویI-131 MIBG در درمان تومورهای با منشأ غددی- عصبی، خصوصاً از نوع نورواکتودرمال (سمپاتوآدرنال) شامل فئوکروموسیتوم، پاراگانگلیوم و نوروبلاستوم مؤثر بوده است. در سایر تومورهای غددی- عصبی (عمدتاً کارسینوئید و کارسینوم مدولاری تیروئید) نیز این درمان گاهی می‌تواند مؤثر واقع گردد. مواد و روش‌ها: در این مطالعه مروری، کارآزمایی‌های بالینی شاهد - موردی و همچنین مطالعات باز که دارای اع...
متن کاملMyocardial iodine-123-metaiodobenzylguanidine (123I-MIBG) imaging in Brugada syndrome.
(I-MIBG) Imaging in Brugada Syndrome To the Editor: We read with interest a recent article in Circulation by Wichter et al1 on cardiac autonomic dysfunction in Brugada syndrome. The authors demonstrated that regionally reduced iodine-123-metaiodobenzylguanidine (I-MIBG) uptake in the inferior and septal left ventricular wall was present in 8 (47%) of 17 patients with Brugada syndrome but in non...
متن کاملLow-dose (123)I-metaiodobenzylguanidine diagnostic scan is inferior to (131)I-metaiodobenzylguanidine posttreatment scan in detection of malignant pheochromocytoma and paraganglioma.
OBJECTIVE We assessed the lesion detectability of low-dose diagnostic (123)I-metaiodobenzylguanidine (MIBG) whole-body scans obtained at 6 and 24 h compared with posttreatment (131)I-MIBG whole-body scans in malignant pheochromocytoma and paraganglioma. METHODS Scintigrams obtained in 15 patients with malignant pheochromocytoma and paraganglioma were retrospectively analyzed. Diagnostic scans...
متن کاملI-131-Metaiodobenzylguanidine therapy with allogeneic cord blood stem cell transplantation for recurrent neuroblastoma
Iodine-131-metaiodiobenzylguanidine (131I-MIBG) therapy combined with allogeneic cord blood stem cell transplantation (SCT) was used to treat a 4-year-old girl with recurrent neuroblastoma. The patient experienced relapse 2 years after receiving first-line therapies, which included chemotherapy, surgical resection, irradiation, and autologous peripheral SCT. Although 131I-MIBG treatment did not...
متن کاملI-metaiodobenzylguanidine myocardial scintigraphy in Parkinson’s disease
Objectives—I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy is clinically used to estimate local myocardial sympathetic nerve damage in some forms of heart disease, autonomic nerve disturbance in diabetic neuropathy, and disturbance of the autonomic nervous system in neurodegenerative disease. In the present study, examinations were performed to clarify (1) the proportion of cardiac sym...
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ژورنال
عنوان ژورنال: Nuclear Medicine Seminars
سال: 2015
ISSN: 2149-6447
DOI: 10.4274/nts.2015.016